A 4-factor full-factorial experiment with 5 levels each requires 5^4 = 625 test points. A Latin Hypercube Design (LHD) with 60 points can cover the same space and still fit a response surface model with quantified uncertainty — a 10× reduction in dyno time while maintaining statistical model quality.
One-Factor-at-a-Time (OFAT): Latin Hypercube Design (LHD):
Fix RPM=2000, sweep EGR 0-40% 60 points: RPM and EGR varied
Fix EGR=20%, sweep RPM 1000-5000 simultaneously, space-filling
Fix both, sweep load No factor held constant
Detects interactions between factors
OFAT: 3 × 20 points = 60 test points LHD: 60 points
OFAT: misses RPM-EGR interaction LHD: captures full joint response
OFAT: cannot fit 2nd-order model LHD: supports Gaussian Process model